Brucellosis as a human threatening and economic disease

Abstract

This review study aimed to collect information about Brucellosis as a disease that has an impact on humans from several aspects, whether from the health or economic aspect.Brucellosis is one of the most common contagious and communicable zoonotic diseases with high rates of morbidity and lifetime sterility, caused by genus Brucella.Brucella is a Gram-negative, aerobic, and facultative intracellular coccobacillus, and due to its complex nature, brucellosis remains a serious threat to public health and livestock in developing countries.There are various diagnostic tests employed for the diagnosis of brucellosis including culture, serological, immunopathological and molecular methods, but the quantitative or real-time polymerase chain reaction (qPCR) assay is specific and highly sensitive and could be an appropriate method for the rapid and safe detection of the genus Brucella