The Incidence of Hypertension in Children with Nephrotic Syndrome in Comparison with Low & High-Risk Group & Associated Risk Factors.

Abstract

Background: Hypertension is com-mon among steroid resistant and ster-oid dependent nephrotic syndrome patients. hypertension is one of the most common sequelae of chronic kidney disease in pediatric age group.Patients & methods: A cross sectional study which was carried out in Neph-rology Department at Central Child Teaching hospital & Al-Karamah Teaching hospital with total of 255 patients included 102 patients with nephrotic syndrome & with measure-ment of blood pressure of 102 child with no history of any disease, this study also included measurement of blood pressure for 51 patients with chronic kidney disease.Results: In this study, the total num-ber of cases of nephrotic syndrome, chronic kidney disease, & normal children were 102, 51, 102 cases re-spectively, male to female ratio was 1.5:1 for both nephrotic syndrome & normal children while it was 1.8:1 for chronic kidney disease patients. hy-pertension was reported in 2 cases only of total 102 cases of normal population & in 33 cases of total 102 cases of nephrotic syndrome While it reported in 29 cases of total 51 cases of chronic kidney disease.Conclusions: Nephrotic syndrome can be considered to be intermediate risk factor for development of hyperten-sion between normal children & chronic kidney disease. Hypertension was found to be more in steroid re-sistant nephrotic syndrome and ster-oid dependent nephrotic syndrome group than in steroid sensitive ne-phrotic syndrome group. hypertension also was found to be more in frequent relapsing nephrotic syndrome. The incidence of hypertension was more in nephrotic patients with elevated blood urea and S.Creatinine than in patient with normal renal function.