Abstract

Phenytion selective electrodes were prepared based on a complex phenytion-phosphomolybdate as an active material using the plasticizers di-octyl phthalate (DOPH), tri-butyl phosphate (TBP), o-nitro phenyl octyl ether (ONPOE) and di-butyl phthalate (DBPH) in a PVC matrix membrane. The properties of the prepared electrodes were studied, such as: slope, concentration range, detection limit, lifetime, pH effect and selectivity. The experimental results showed that the best electrode was based on DOPH and DBPH as plasticizers, displaying a linear range from1.00 x 10−4 M to 1.00 x 10−1 M and 1.00 x10−1 M to 5 x10−4 with a Nernstian slope of 58.5 mV/decade and 55.8 mV/decade, correlation coefficient of 0.9997 and 0.9998, The detection limit was 5.5 x 10−5 M and 8.0 x10−5, the lifetime was around 60 and 45 days respectively. The proposed electrodes were successfully applied to the determination of phenytion in a pharmaceutical preparation.

The article was added to IASJ on 2013-01-31

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